EPIDERMAL GROWTH-FACTOR RECEPTOR IN BREAST-CANCER - COMPARISON WITH NONMALIGNANT BREAST-TISSUE

被引：44

作者：

DITTADI, R

DONISI, PM

BRAZZALE, A

CAPPELLOZZA, L

BRUSCAGNIN, G

GION, M

机构：

[1] REG GEN HOSP VENICE,CTR STUDY BIOL MARKERS MALIGNANCY,ULSS 16,VENICE,ITALY

[2] REG GEN HOSP VENICE,SERV PATHOL ANAT,VENICE,ITALY

来源：

BRITISH JOURNAL OF CANCER | 1993年 / 67卷 / 01期

关键词：

D O I：

10.1038/bjc.1993.2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Epidermal growth factor receptors were measured using a radioligand binding assay in membrane preparations from 67 cancer and 25 non-malignant tissues. The binding characteristics of EGFr were similar in tumour and normal breast membranes. The concentrations were significantly higher in non-malignant tissue than in cancer. EGFr concentrations were directly correlated with steroid receptors in non-malignant tissue, whereas in cancer an inverse correlation between EGFr and steroid receptors was found.

引用

页码：7 / 9

页数：3

共 11 条

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