PAPAIN-CATALYZED POLYMERIZATION OF AMINO-ACIDS IN LOW WATER ORGANIC-SOLVENTS

被引：7

作者：

FERJANCIC, A ^{[1
]}

PUIGSERVER, A ^{[1
]}

GAERTNER, H ^{[1
]}

机构：

[1] CNRS,CTR BIOCHIM & BIOL MOLEC,BP 71,F-13402 MARSEILLE 9,FRANCE

来源：

BIOTECHNOLOGY LETTERS | 1991年 / 13卷 / 03期

关键词：

D O I：

10.1007/BF01025811

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Polyethylene glycol-modified papain catalyzed the oligomerization of amino acid amides in toluene. The water content of the organic solvent was a critical factor determining the extent of polymerization. Under optimized conditions, lysine and phenylalanine oligomers containing up to 10 residues were obtained. In sharp contrast to what is observed in aqueous media, hydrophilic and basic amino acid derivatives resulted in higher reaction yields than hydrophobic amino acid derivatives.

引用

页码：161 / 166

页数：6

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