INVITRO INVIVO CORRELATION FOR MODIFIED-RELEASE FORMULATIONS

被引：20

作者：

DREWE, J

GUITARD, P

机构：

[1] UNIV HOSP BASEL, KANTONSSPITAL, DEPT RES, CH-4031 BASEL, SWITZERLAND

[2] SANDOZ PHARMA LTD, PHARMA DEV, BASEL, SWITZERLAND

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1993年 / 82卷 / 02期

关键词：

D O I：

10.1002/jps.2600820204

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A correlation of in vitro dissolution rate measurements with in vivo pharmacokinetic results in a human study was obtained for a sustained-release formulation of bromocriptine. Different methods were applied to reach this correlation, and the various outcomes were compared.

引用

收藏

页码：132 / 137

页数：6

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