HEATING AT 56-DEGREES-C DOES NOT ELIMINATE IMMUNE COMPLEX-BOUND CLQ

被引：8

作者：

TEPPO, AM ^{[1
]}

WAGER, O ^{[1
]}

机构：

[1] AURORA HOSP,MUNICIPAL BACTERIOL LAB,SF-00250 HELSINKI 25,FINLAND

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1979年 / 10卷 / 05期

关键词：

D O I：

10.1111/j.1365-3083.1979.tb01372.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The effect of heating at 56°C on free and complex‐bound human Clq was studied by radioisotope and sucrose gradient centrifugation techniques. The ability of soluble complexes of egg albumin, rabbit anti‐egg albumin, and human Clq to bind extrinsic iodinated Clq did not increase following heating at 56°C. The results of this study did not support the postulated release of complex‐bound Clq on healing at 56°C. They also showed that free Clq was more heat‐labile than Clq in the Clqrs state. The importance of elimination or monitoring of intrinsic Clq in Clq assays for circulating immune complexes is stressed. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：431 / 435

页数：5

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