LESSONS FROM LETHAL ALBINO MICE

被引：13

作者：

KELSEY, G ^{[1
]}

SCHUTZ, G ^{[1
]}

机构：

[1] GERMAN CANC RES CTR, W-6900 HEIDELBERG 1, GERMANY

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 02期

关键词：

D O I：

10.1016/0959-437X(93)90032-K

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Results from the analysis of mice homozygous for lethal albino deletions suggested the existence of a locus involved in the regulation of gene expression in the liver. The surprising finding that the locus encodes an enzyme active in tyrosine metabolism forces us to re-evaluate the lethal albino phenotype and advises caution in the interpretation of seemingly simple phenotypes.

引用

页码：259 / 264

页数：6

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