AN AUSTRALIA-WIDE EPIDEMIC OF PSEUDOMONAS-PICKETTII BACTEREMIA DUE TO CONTAMINATED STERILE WATER FOR INJECTION

被引：52

作者：

ROBERTS, LA

COLLIGNON, PJ

CRAMP, VB

ALEXANDER, S

MCFARLANE, AE

GRAHAM, E

FULLER, A

SINICKAS, V

HELLYAR, A

机构：

[1] ROYAL CANBERRA HOSP,DEPT MICROBIOL,ACTON,ACT 2601,AUSTRALIA

[2] ROYAL CANBERRA HOSP,PHARM SERV,ACTON,ACT 2601,AUSTRALIA

[3] WODEN VALLEY HOSP,PHARM SERV,GARRAN,ACT 2605,AUSTRALIA

[4] WODEN VALLEY HOSP,DEPT MICROBIOL,ACT CENT HLTH LAB,GARRAN,ACT 2605,AUSTRALIA

[5] THERAPEUT GOODS ADM LABS,CANBERRA,ACT 2601,AUSTRALIA

[6] ROYAL MELBOURNE HOSP,DEPT MICROBIOL,PARKVILLE,VIC 3050,AUSTRALIA

来源：

MEDICAL JOURNAL OF AUSTRALIA | 1990年 / 152卷 / 12期

关键词：

D O I：

10.5694/j.1326-5377.1990.tb125422.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nineteen cases of Pseudomonas pickettii bacteraemia and one case of Pseudomonas cepacia bacteraemia were identified in an Australia-wide outbreak of nosocomial sepsis associated with contaminated water for injection. The contamination was limited to one batch of commercially produced water for injection. Four different organisms were identified (three biotypes of P. pickettii and one of P. cepacia). However, P. pickettii biotype 1 appeared to be relatively more virulent than the other biotypes as it was the only identified organism in blood cultures in nearly all cases of sepsis. The ampoules of 'sterile' water were each contaminated with approximately 103 organisms per millilitre. The lack of an Australian central reporting system for bacteraemia delayed the recognition of this outbreak.

引用

页码：652 / 655

页数：4

共 21 条

[1] RAPID DIAGNOSIS OF INTRAVASCULAR CATHETER-RELATED SEPSIS [J].