Step-by-Step Build-Up of Biologically Active Cell-Containing Stratified Films Aimed at Tissue Engineering

被引：35

作者：

Grossin, Laurent ^{[2
,3
]}

Cortial, Delphine ^{[4
]}

Saulnier, Benjamin ^{[5
]}

Felix, Olivier ^{[5
]}

Chassepot, Armelle ^{[4
]}

Decher, Gero ^{[5
]}

Netter, Patrick ^{[2
,3
]}

Schaaf, Pierre ^{[5
]}

Gillet, Pierre ^{[2
,3
]}

Mainard, Didier ^{[2
,3
]}

Voegel, Jean-Claude ^{[1
]}

Benkirane-Jessel, Nadia ^{[1
]}

机构：

[1] INSERM, U595, Fac Med, F-67085 Strasbourg, France

[2] Univ Nancy 1, Unite Mixte Rech 7561, Ctr Natl Rech Sci, Fac Med, Vandoeuvre Les Nancy, France

[3] Hop Cent, Ctr Hosp Univ Nancy, F-54000 Nancy, France

[4] Univ Strasbourg, Fac Chirurg Dent, F-67000 Strasbourg, France

[5] Univ Strasbourg, Inst Charles Sadron, CNRS UPR 22, F-67034 Strasbourg, France

来源：

ADVANCED MATERIALS | 2009年 / 21卷 / 06期

关键词：

POLYELECTROLYTE MULTILAYER FILMS; EXPONENTIAL-GROWTH; THIN-FILMS; LAYERS; SCAFFOLDS; CYCLODEXTRIN; TECHNOLOGY; ASSEMBLIES; SURFACES; COATINGS;

D O I：

10.1002/adma.200801541

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Alginate gel layers containing viable cells with adjacent bioactive polyelectrolyte multilayers are fabricated, and their bioactivity is shown to originate mainly from the degradation of the cells. Alternate biofunctionalized multilayers and cell-containing layers are shown to be an essential step toward fabrication of stratified architectures, and tuning the cellular activity is possible by controlling the position of active molecules.

引用

页码：650 / +

页数：7

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