MACROGLOBULIN STRUCTURE - HOMOLOGY OF MU AND GAMMA HEAVY CHAINS OF HUMAN IMMUNOGLOBULINS

被引：97

作者：

WIKLER, M

KOHLER, H

SHINODA, T

PUTNAM, FW

机构：

来源：

SCIENCE | 1969年 / 163卷 / 3862期

关键词：

D O I：

10.1126/science.163.3862.75

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The amino acid sequence of fragments obtained by cyanogen bromide cleavage of the mu-chain of a human γM-globulin is homologous to the NH2-terminal sequences of the gamma-chain of human and rabbit γG-globulins and is related to that of human light chains. This supports the hypothesis that light and heavy chains evolved from a common ancestral gene.

引用

页码：75 / &

共 22 条

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