INTRARECTAL METRONIDAZOLE IN THE PREVENTION OF ANAEROBIC INFECTIONS AFTER EMERGENCY APPENDECTOMY - CONTROLLED CLINICAL-TRIAL

被引：49

作者：

RODGERS, J

ROSS, D

MCNAUGHT, W

GILLESPIE, G

机构：

[1] VICTORIA INFIRM,DEPT SURG,GLASGOW,SCOTLAND

[2] VICTORIA INFIRM,DEPT BACTERIOL,GLASGOW,SCOTLAND

来源：

BRITISH JOURNAL OF SURGERY | 1979年 / 66卷 / 06期

关键词：

D O I：

10.1002/bjs.1800660616

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A series of 102 patients with presumptive acute appendicitis entered a prospective, randomized, clinical trial of intrarectal metronidazole given over a 48‐h period commencing before surgery. Adequate levels of circulating metronidazole were achieved. A significant reduction in the incidence of anaerobic wound infection was observed in the treated group (P < 0.02). The convenience and short duration of the prophylactic regimen allowed early discharge from hospital. No untoward effects were observed. Copyright © 1979 British Journal of Surgery Society Ltd.

引用

页码：425 / 427

页数：3

共 4 条

[1]

Cowan ST., 1974, COWAN STEELS MANUAL, V2, P67

[2]

GOLDRING J, 1975, LANCET, V2, P997

[3] METRONIDAZOLE IN PREVENTION AND TREATMENT OF BACTEROIDES INFECTIONS AFTER APPENDECTOMY [J].

WILLIS, AT ;

FERGUSON, IR ;

JONES, PH ;

PHILLIPS, KD ;

TEARLE, PV ;

BERRY, RB ;

FIDDIAN, RV ;

GRAHAM, DF ;

HARLAND, DHC ;

INNES, DB ;

MEE, WM ;

ROTHWELLJACKSON, RL ;

SUTCH, I ;

KILBEY, C ;

EDWARDS, D .

BRITISH MEDICAL JOURNAL, 1976, 1 (6005) :318-321

[4] METRONIDAZOLE IN PREVENTION AND TREATMENT OF BACTEROIDES INFECTIONS IN ELECTIVE COLONIC SURGERY [J].

WILLIS, AT ;

FERGUSON, IR ;

JONES, PH ;

PHILLIPS, KD ;

TEARLE, PV ;

FIDDIAN, RV ;

GRAHAM, DF ;

HARLAND, DHC ;

HUGHES, DFR ;

KNIGHT, D ;

MEE, WM ;

PASHBY, N ;

ROTHWELLJACKSON, RL ;

SACHDEVA, AK ;

SUTCH, I ;

KILBEY, C ;

EDWARDS, D .

BRITISH MEDICAL JOURNAL, 1977, 1 (6061) :607-610

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