共 20 条
PRODUCTION OF COLONIZATION FACTOR ANTIGEN-II OF ENTEROTOXIGENIC ESCHERICHIA-COLI IS SUBJECT TO CATABOLITE REPRESSION
被引:7
作者:
EVANS, DG
EVANS, DJ
KARJALAINEN, TK
LEE, CH
机构:
[1] BAYLOR UNIV,DEPT MED,HOUSTON,TX 77030
[2] INDIANA UNIV,SCH MED,DEPT PATHOL,INDIANAPOLIS,IN 46202
关键词:
D O I:
10.1007/BF02092252
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Experiments were performed to study the effect of glucose on the production of the fimbrial colonization factor CFA/II of enterotoxigenic Escherichia coli (ETEC). The production of the CFA/II antigen was examined by electron microscopy, quantitative ELISA, and hemagglutination. The results showed that addition of 1% glucose to the growth medium drastically decreased CFA/II production, whereas addition of glycerol or sodium acetate did not have any effect. Bacteria grown in the presence of 1% glucose were essentially devoid of CFA/II fimbriae when examined under the electron microscope. Addition of 1 mM cAMP reversed the repressive effect of glucose, suggesting that the glucose suppression on CFA/II synthesis is via the mechanism of catabolite repression.
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页码:71 / 74
页数:4
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