REVERSE-PHASE HPLC DETERMINATION OF THIORIDAZINE AND MESORIDAZINE IN WHOLE-BLOOD

被引：8

作者：

MCCUTCHEON, JR

机构：

[1] Toxicology Section, Texas Department of Public Safety Crime Laboratory, Austin, TX

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1979年 / 3卷 / 03期

关键词：

D O I：

10.1093/jat/3.3.105

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A reverse-phase high performance liquid chromatography method for the analysis of the antipsychotic drugs thioridazine and mesoridazine is described. Aqueous standard solutions and spiked whole human blood specimens ranging in concentration from therapeutic to toxic overdose levels were analyzed using trifluoperazine as an internal standard. The minimum detection limit is 0.25 mg/l in 2 ml of blood.

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页码：105 / 107

页数：3

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