THE SEQUENCE OF A HUMAN MITOCHONDRIAL GLYCEROL-3-PHOSPHATE DEHYDROGENASE-ENCODING CDNA

被引：22

作者：

LEHN, DA ^{[1
]}

BROWN, LJ ^{[1
]}

SIMONSON, GD ^{[1
]}

MORAN, SM ^{[1
]}

MACDONALD, MJ ^{[1
]}

机构：

[1] UNIV WISCONSIN,SCH MED,CTR CHILDRENS DIABET,MADISON,WI 53706

来源：

GENE | 1994年 / 150卷 / 02期

关键词：

HUMAN CDNA LIBRARY; HELA CELL; NUCLEAR ENCODED; AMINO-ACID HOMOLOGY; CALCIUM-BINDING SITES;

D O I：

10.1016/0378-1119(94)90469-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A 2618-bp cDNA that encodes the human mitochondrial glycerol-3-phosphate dehydrogenase has been isolated from a HeLa cell cDNA library and the nucleotide sequence determined. An open reading frame encodes a protein of 727 amino acids that is 96% similar to the rat protein and, like the rat protein, contains sites homologous to the Ca2+ binding sites of calmodulin, as well as FAD- and putative glycerol-phosphate-binding sites.

引用

页码：417 / 418

页数：2