NEUTRAL LIPID AND SPHINGOLIPID COMPOSITION OF THE BRAIN OF A PATIENT WITH MEMBRANOUS LIPODYSTROPHY

被引:9
作者
OHTANI, Y [1 ]
MIURA, S [1 ]
TAMAI, Y [1 ]
KOJIMA, H [1 ]
KASHIMA, H [1 ]
机构
[1] KEIO UNIV, SCH MED, DEPT NEUROPSYCHIAT, TOKYO 160, JAPAN
关键词
Cholesterol; Demyelination; Free fatty acid; Lipodystrophy; Sphingolipid;
D O I
10.1007/BF00313947
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Lipids were extracted from brains of a patient with membranous lipodystrophy (ML) and three normal patients and the neutral lipid and sphingolipid constituents were investigated. The storage of a large amount of free fatty acid was observed in the ML brain, but no cholesterol ester was found. Total lipid, cholesterol and cerebroside contents were slightly decreased in the white matter of the ML brain. The compositions of free and sphingolipid fatty acids did not differ between ML and normal brains. © 1979 Springer-Verlag.
引用
收藏
页码:77 / 82
页数:6
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