CANCER GROWTH, RESPONSE TO TREATMENT AND SURVIVAL TIME IN MICE - BENEFICIAL EFFECT OF THE PROSTAGLANDIN SYNTHESIS INHIBITOR FLURBIPROFEN

被引：82

作者：

BENNETT, A

HOUGHTON, J

LEAPER, DJ

STAMFORD, IF

机构：

[1] Department of Surgery, King's College Hospital Medical School, London

来源：

PROSTAGLANDINS | 1979年 / 17卷 / 02期

关键词：

D O I：

10.1016/0090-6980(79)90037-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Adult mice were injected subcutaneously with cells from a syngeneic metastasizing mammary cancer. Daily treatment with flurbiprofen starting before injection of the cancer cells reduced tumour growth and lengthened the survival of mice whose tumours were excised at 3 weeks. When low doses of radiotherapy and chemotherapy were given, additional treatment with flurbiprofen starting 25 days after injecting the cancer cells substantially inhibited tumour growth. © 1979.

引用

页码：179 / 191

页数：13

共 25 条

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