WHEAT-GERM AGGLUTININ ACTIVATES MACROPHAGES FOR COLLABORATION WITH B-CELLS

被引:8
作者
BERNABE, RR
MARTINEZALONSO, C
LARSSON, EL
COUTINHO, A
机构
[1] BASEL INST IMMUNOL,CH-4005 BASEL 5,SWITZERLAND
[2] CLIN PUERTA HIERRO,DEPT IMMUNOL,MADRID,SPAIN
关键词
D O I
10.1002/eji.1830090816
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Wheat germ agglutinin (WGA), added to Mishell‐Dutton‐type cultures of nude spleen cells challenged with erythrocyte antigens, allows a primary specific plaque‐ forming cell (PFC) response. WGA, however, does not display direct mitogenicity to either T or B lymphocytes. The activity of WGA in the specific PFC response is macrophage‐dependent and parallels a nonspecific PFC response in the same cultures. Copyright © 1979 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
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页码:654 / 656
页数:3
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