A TECHNIQUE FOR STABLE ADHESION OF DNA TO A MODIFIED GRAPHITE SURFACE FOR IMAGING BY SCANNING TUNNELING MICROSCOPY

被引：33

作者：

LYUBCHENKO, YL ^{[1
]}

LINDSAY, SM ^{[1
]}

DEROSE, JA ^{[1
]}

THUNDAT, T ^{[1
]}

机构：

[1] ARIZONA STATE UNIV,DEPT PHYS,TEMPE,AZ 85287

来源：

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B | 1991年 / 9卷 / 02期

关键词：

D O I：

10.1116/1.585223

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A procedure has been developed in which mercurated DNA is covalently bonded to a modified graphite surface. This technique allows for stable adhesion of the DNA which enables one to image it with the scanning tunneling microscope. The method is outlined in this paper and images are presented of a partially modified graphite surface and one completely modified with DNA attached. The DNA images demonstrate B-helix periodicity.

引用

页码：1288 / 1290

页数：3

共 7 条

[1] MERCURATED POLYNUCLEOTIDES - NEW PROBES FOR HYBRIDIZATION AND SELECTIVE POLYMER FRACTIONATION [J].