USE OF POLYMERASE CHAIN-REACTION NAD DENATURING GRADIENT GEL-ELECTROPHORESIS TO IDENTIFY POLYMORPHISMS IN 3 EXONS OF DOPAMINE-D2 RECEPTOR GENE IN SCHIZOPHRENIC AND DELUSIONAL PATIENTS

The dopamine D2 receptor gene is a candidate gene for schizophrenia. We screened three exons of this gene for mutations in a large sample of schizophrenics, delusional patients and healthy controls. No structural changes were found, thus suggesting that psychopathology is not related to DNA alterations in the DRD2 gene.