CALCIPHYLAXIS IN A HEMODIALYSIS PATIENT - APPEARANCE AFTER PARATHYROIDECTOMY DURING A PSORIATIC FLARE

被引：27

作者：

POCH, E ^{[1
]}

ALMIRALL, J ^{[1
]}

ALSINA, M ^{[1
]}

DELRIO, R ^{[1
]}

CASES, A ^{[1
]}

REVERT, L ^{[1
]}

机构：

[1] UNIV BARCELONA,HOSP CLIN & PROV,DERMATOL SERV,BARCELONA 7,SPAIN

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 1992年 / 19卷 / 03期

关键词：

CALCIPHYLAXIS; CHRONIC RENAL FAILURE; HYPERPARATHYROIDISM; PSORIASIS;

D O I：

10.1016/S0272-6386(13)80011-X

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic renal failure patients are prone to soft tissue calcifications. A phenomenon of acute ischemic skin necrosis and dermohypodermic arteriolar medial calcification has been described recently in patients with chronic renal failure and secondary hyperparathyroidism (HPT). This phenomenon, termed calciphylaxis, occurs in response to certain factors, the most important of which appears to be an elevated blood calcium-phosphate product. Accordingly, parathyroidectomy in addition to normalization of calcium-phosphate product has been proposed as the only effective therapeutic approach for this condition. We describe a case of chronic renal failure with severe secondary HPT in which the patient developed calciphylaxis 4 days after the appearance of a psoriatic flare. Four months before, a subtotal parathyroidectomy was performed for severe HPT and at the time the ulcerations appeared, blood calciumphosphate product was correct. Etiological and physiopathological aspects of calciphylaxis are discussed. © 1992, National Kidney Foundation. All rights reserved.. All rights reserved.

引用

页码：285 / 288

页数：4

共 19 条

[1] SUCCESSFUL TREATMENT OF ISCHEMIC ULCERATION OF SKIN IN AZOTEMIC HYPERPARATHYROIDISM WITH PARATHYROIDECTOMY [J].

BLUMBERG, A ;

WEIDMANN, P .

BRITISH MEDICAL JOURNAL, 1977, 1 (6060) :552-553

[2] THE VASCULAR-LESIONS ASSOCIATED WITH SKIN NECROSIS IN RENAL-DISEASE [J].

CHAN, YL ;

MAHONY, JF ;

TURNER, JJ ;

POSEN, S .

BRITISH JOURNAL OF DERMATOLOGY, 1983, 109 (01) :85-95

[3] CALCIPHYLAXIS - ETIOLOGY OF PROGRESSIVE VASCULAR CALCIFICATION AND GANGRENE [J].

CONN, J ;

KRUMLOVSKY, FA ;

DELGRECO, F ;

SIMON, NM .

ANNALS OF SURGERY, 1973, 177 (02) :206-210

[4] POST-RENAL TRANSPLANT CALCIPHYLAXIS - SUCCESSFUL TREATMENT WITH PARATHYROIDECTOMY [J].

FOX, R ;

BANOWSKY, LH ;

CRUZ, AB .

JOURNAL OF UROLOGY, 1983, 129 (02) :362-363

[5] CALCIPHYLAXIS IN MAN - SYNDROME OF TISSUE NECROSIS AND VASCULAR CALCIFICATION IN 11 PATIENTS WITH CHRONIC RENAL-FAILURE [J].

GIPSTEIN, RM ;

COBURN, JW ;

ADAMS, DA ;

LEE, DBN ;

PARSA, KP ;

SELLERS, A ;

SUKI, WN ;

MASSRY, SG .

ARCHIVES OF INTERNAL MEDICINE, 1976, 136 (11) :1273-1280

[6] CALCIFYING PANNICULITIS AND KIDNEY FAILURE - CONSIDERATIONS ON PATHOGENESIS AND TREATMENT OF CALCIPHYLAXIS [J].

GROB, JJ ;

LEGRE, R ;

BERTOCCHIO, P ;

PAYAN, MJ ;

ANDRAC, L ;

BONERANDI, JJ .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1989, 28 (02) :129-131

[7] CALCINOSIS CUTIS AND RENAL-FAILURE [J].

KOLTON, B ;

PEDERSEN, J .

ARCHIVES OF DERMATOLOGY, 1974, 110 (02) :256-257

[8]

LEVER WF, 1983, HISTOPATHOLOGY SKIN, P420

[9] VASCULAR CALCIFICATION AND PERIPHERAL NECROSIS IN A RENAL TRANSPLANT RECIPIENT - REVERSAL OF LESIONS FOLLOWING SUBTOTAL PARATHYROIDECTOMY [J].

MASSRY, SG ;

GORDON, A ;

COBURN, JW ;

KAPLAN, L ;

FRANKLIN, SS ;

MAXWELL, MH ;

KLEEMAN, CR .

AMERICAN JOURNAL OF MEDICINE, 1970, 49 (03) :416-+

[10] SKIN NECROSIS ASSOCIATED WITH ACQUIRED PROTEIN-C DEFICIENCY IN PATIENTS WITH RENAL-FAILURE AND CALCIPHYLAXIS [J].

MEHTA, RL ;

SCOTT, G ;

SLOAND, JA ;

FRANCIS, CW .

AMERICAN JOURNAL OF MEDICINE, 1990, 88 (03) :252-257

← 1 2 →