ESTRADIOL BINDING IN THE SEXUALLY DIMORPHIC NUCLEUS OF THE PREOPTIC ANTERIOR HYPOTHALAMIC AREA OF ADULT MALE FERRETS AND IN THE EQUIVALENT REGION OF FEMALES

被引：12

作者：

TOBET, SA

BAUM, MJ

机构：

[1] HARVARD UNIV,SCH MED,PROGRAM NEUROSCI,BOSTON,MA 02115

[2] BOSTON UNIV,DEPT BIOL,BOSTON,MA 02215

来源：

BRAIN RESEARCH | 1991年 / 546卷 / 02期

关键词：

ESTROGEN RECEPTOR; SEXUALLY DIMORPHIC NUCLEUS; FERRET; STEROID AUTORADIOGRAPHY;

D O I：

10.1016/0006-8993(91)91500-Z

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A large number of estradiol-concentrating cells were visualized by autoradiography in a subpopulation of large neurons located in and around the sexually dimorphic male nucleus of the preoptic/anterior hypothalamic area (MN-POA/AH) of castrated male ferrets and in a comparable dorsal portion of the POA/AH of ovariectomized females. Considerably fewer estradiol-labelled cells were seen in the non-dimorphic ventral POA/AH nucleus of both sexes. Estrogen binding in cells in or around the MN-POA/AH may contribute to the formation of this sexually dimorphic nucleus in fetal males and may mediate specific estrogen-dependent behavioral functions in adulthood.

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收藏

页码：345 / 350

页数：6

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