IGG ANTIGANGLIOSIDE ANTIBODIES AND THEIR SUBCLASS DISTRIBUTION IN 2 PATIENTS WITH ACUTE AND CHRONIC MOTOR NEUROPATHY

被引：14

作者：

GUIJO, CG

GARCIAMERINO, A

RUBIO, G

GUERRERO, A

MARTINEZ, AC

ARPA, J

机构：

[1] CLIN PUERTA HIERRO,DEPT NEUROL,MADRID,SPAIN

[2] HOSP LA PAZ,DEPT NEUROPHYSIOL,MADRID,SPAIN

[3] HOSP CLIN MADRID,DEPT NEUROL,MADRID,SPAIN

[4] HOSP LA PAZ,DEPT NEUROL,MADRID,SPAIN

来源：

JOURNAL OF NEUROIMMUNOLOGY | 1992年 / 37卷 / 1-2期

关键词：

ANTIGANGLIOSIDE ANTIBODY; IGG SUBCLASS; MOTOR NEUROPATHY;

D O I：

10.1016/0165-5728(92)90165-H

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

IgG anti-ganglioside antibodies were found in two patients with motor neuropathy. The first patient had a chronic axonal neuropathy with persistently elevated anti-G(M1) antibodies. The second patient had an acute axonal neuropathy with anti-G(M1), G(D1b) and asialoG(M1) antibodies. In both, the IgG subclass study showed that the antibodies belonged to the IgG1 subclass. An enzyme-linked immunosorbent assay (ELISA) for light chains revealed anti-ganglioside antibodies of the lambda type.

引用

页码：141 / 148

页数：8

共 19 条

[1]

ADAMS S, 1990, NEUROLOGY S1, V1, P299

[2]

BABA H, 1988, T AM SOC NEUROCHEM, V19, P103

[3]

FREDDO L, 1986, NEUROLOGY, V36, P454, DOI 10.1212/WNL.36.4.454

[4] IDENTIFICATION AND CHARACTERIZATION OF GANGLIOSIDES REACTING WITH IGM PARAPROTEINS IN 3 PATIENTS WITH NEUROPATHY ASSOCIATED WITH BICLONAL GAMMOPATHY [J].