CENTRIFUGAL PARTITION CHROMATOGRAPHY - STABILITY OF VARIOUS BIPHASIC SYSTEMS AND PERTINENCE OF THE STOKES MODEL TO DESCRIBE THE INFLUENCE OF THE CENTRIFUGAL FIELD UPON THE EFFICIENCY

The stability of various biphasic systems has been determined using a High Performance Centrifugal Partition Chromatograph, and its relationship with various physical parameters has been estimated. The stability seems to be related to gamma/Delta rho, the ratio of the interfacial tension to that of the density difference between the two phases, and which is a parameter accounting for both the ''Stoke's radius'' of the mobile phase, i.e, the radius of droplets of mobile phase which will have the same average linear velocity. ($) over bar u, in the channels than the experimentally determined value, and the ''fragility'' of these droplets. The average linear velocity of the mobile phase is not dependent upon the acceleration field in the range studied, which means that, using the ''Stoke's model'' (droplets, even if they do not exist), the higher the acceleration field, the smaller the droplets, Consequently, there is a linear relationship between the efficiency and the rotational speed, provided all other parameters are kept constant.