MOLECULAR-CLONING OF AN ALPHA(1)-SUBUNIT FROM HOUSEFLY (MUSCA-DOMESTICA) MUSCLE

被引：36

作者：

GRABNER, M

BACHMANN, A

ROSENTHAL, F

STRIESSNIG, J

SCHULZ, C

TAUTZ, D

GLOSSMANN, H

机构：

[1] UNIV INNSBRUCK, INST BIOCHEM PHARMAKOL, A-6020 INNSBRUCK, AUSTRIA

[2] UNIV MUNICH, INST ZOOL, W-8000 MUNICH 2, GERMANY

来源：

FEBS LETTERS | 1994年 / 339卷 / 1-2期

关键词：

CALCIUM CHANNEL; CDNA CLONING; HYBRIDIZATION (IN SITU); BODY WALL MUSCLE; PHYLOGENETIC TREE;

D O I：

10.1016/0014-5793(94)80413-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The complete amino acid sequence of an invertebrate calcium channel alpha-subunit from housefly (Musca domestica) larvae (designated Mdl alpha(1)) has been deduced by cDNA cloning and sequence analysis. Mdbl alpha(1) shares higher percent sequence identity with 1,4-dihydropyridine (DHP)-sensitive L-type than with DHP-insensitive calcium channels. As shown by whole mount in situ hybridization and immunostaining Mdl alpha(1) is predominantly expressed in the larval body wall musculature.

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页码：189 / 194

页数：6

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