ANTITUMOR AGENTS FROM BURSERA MICROPHYLLA (BURSERACEAE) .2. ISOLATION OF A NEW LIGNAN - BURSERAN

被引：47

作者：

COLE, JR

BIANCHI, E

TRUMBULL, ER

机构：

[1] Division of Pharmaceutical Chemistry, College of Pharmacy, University of Arizona, Tucson, Arizona

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 02期

关键词：

Antitumor agents—Bursera microphylla; Burseran—structure identification; IR spectrophotometry—structure; Mass spectroscopy—structure; NMR spectroscopy—structure;

D O I：

10.1002/jps.2600580204

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Bursera microphylla (Burseraceae) A. Gray has yielded a second component which has demonstrated activity in the cell culture test system of the Cancer Chemotherapy National Service Center (CCNSC). On the basis of NMR, mass, and IR spectrometry, the structure of a new lignan, 3‐(3,4‐methylenedioxybenzyl)‐4‐(3“,4”,5‐trimethoxybenzyl) tetrahydrofuran (named burseran), is proposed. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：175 / &