SPONTANEOUSLY PRODUCTIVE C-TYPE RETROVIRUS INFECTION OF FISH CELL-LINES

被引：92

作者：

FRERICHS, GN ^{[1
]}

MORGAN, D ^{[1
]}

HART, D ^{[1
]}

SKERROW, C ^{[1
]}

ROBERTS, RJ ^{[1
]}

ONIONS, DE ^{[1
]}

机构：

[1] UNIV GLASGOW, SCH VET, DEPT VET PATHOL, GLASGOW G61 1QH, SCOTLAND

来源：

JOURNAL OF GENERAL VIROLOGY | 1991年 / 72卷

关键词：

D O I：

10.1099/0022-1317-72-10-2537

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The spontaneous production and release of morphologically typical, 85 to 90 nm diameter C-type retrovirus particles from four cell lines derived from three species of warm-water fish have been identified. Virus pellets from cell culture supernatants showed high levels of Mn2+-dependent reverse transcriptase activity at 24-degrees-C. Peak enzyme activity was associated with a 1.16 g/ml sucrose gradient fraction. All four isolates induced a cytolytic infection of a bluegill fry cell line within 6 to 10 days.

引用

页码：2537 / 2539

页数：3

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