DESIGN OF NEW ANTIHYPERTENSIVE DRUGS - POTENT AND SPECIFIC INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME

被引：82

作者：

CUSHMAN, DW ^{[1
]}

CHEUNG, HS ^{[1
]}

SABO, EF ^{[1
]}

ONDETTI, MA ^{[1
]}

机构：

[1] SQUIBB INST MED RES, POB 4000, PRINCETON, NJ 08540 USA

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 1978年 / 21卷 / 03期

关键词：

D O I：

10.1016/0033-0620(78)90023-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：176 / 181

页数：6

共 25 条

[1] BINDING OF BY-PRODUCT ANALOG BENZYLSUCCINIC ACID BY CARBOXYPEPTIDASE A [J].

BYERS, LD ;

WOLFENDEN, R .

BIOCHEMISTRY, 1973, 12 (11) :2070-2078

[2] POSSIBLE ROLE OF RENIN IN HYPERTENSION AS SUGGESTED BY RENIN-SODIUM PROFILING AND INHIBITION OF CONVERTING ENZYME [J].

CASE, DB ;

WALLACE, JM ;

KEIM, HJ ;

WEBER, MA ;

SEALEY, JE ;

LARAGH, JH .

NEW ENGLAND JOURNAL OF MEDICINE, 1977, 296 (12) :641-646

[3] INHIBITION O HOMOGENEOUS ANGIOTENSIN-CONVERTING ENZYME OF RABBIT LUNG BY SYNTHETIC VENOM PEPTIDES OF BOTHROPS-JARARACA [J].

CHEUNG, HS ;

CUSHMAN, DW .

BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 293 (02) :451-463

[4] INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME BY ANALOGS OF PEPTIDES FROM BOTHROPS-JARARACA VENOM [J].

CUSHMAN, DW ;

PLUSCEC, J ;

WILLIAMS, NJ ;

WEAVER, ER ;

SABO, EF ;

KOCY, O ;

CHEUNG, HS ;

ONDETTI, MA .

EXPERIENTIA, 1973, 29 (08) :1032-1035

[5] DESIGN OF POTENT COMPETITIVE INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME - CARBOXYALKANOYL AND MERCAPTOALKANOYL AMINO-ACIDS [J].

CUSHMAN, DW ;

CHEUNG, HS ;

SABO, EF ;

ONDETTI, MA .

BIOCHEMISTRY, 1977, 16 (25) :5484-5491

[6] SPECTROPHOTOMETRIC ASSAY AND PROPERTIES OF ANGIOTENSIN-CONVERTING ENZYME OF RABBIT LUNG [J].

CUSHMAN, DW ;

CHEUNG, HS .

BIOCHEMICAL PHARMACOLOGY, 1971, 20 (07) :1637-+

[7]

DAS M, 1975, J BIOL CHEM, V250, P6762

[8]

DAVIS JO, 1975, CLIN SCI MOL MED, V48, pS3

[9]

ENGEL SL, 1973, P SOC EXP BIOL MED, V143, P483

[10]

ENGEL SL, 1972, P SOC EXP BIOL MED, V140, P240

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