CONGENITAL UNILATERAL HYDRONEPHROSIS IN THE RAT

被引:29
作者
FRIEDMAN, J [1 ]
HOYER, JR [1 ]
MCCORMICK, B [1 ]
LEWY, JE [1 ]
机构
[1] CORNELL UNIV,COLL MED,DEPT PEDIAT,DIV PEDIAT NEPHROL,NEW YORK,NY 10021
基金
美国国家卫生研究院;
关键词
D O I
10.1038/ki.1979.72
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Hydronephrosis in animals has been noted periodically. Two reports have described strains of rats with unilateral right hydronephrosis, whereas others have reported variably right- or left-sided unilateral hydronephrosis or bilateral hydronephrosis. Detailed studies of the physiologic alterations in a colony of animals with congenital hydronephrosis have not been reported. We have developed a colony of albino rats with congenital, physiologically significant, persistent, unilateral hydronephrosis suitable for such studies. The lesion in this colony has been stable over several generations of breeding.
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页码:567 / 571
页数:5
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