3-DIMENSIONAL STRUCTURE OF TUBULIN PROTOFILAMENTS

被引：91

作者：

AMOS, LA

BAKER, TS

机构：

[1] MRC Laboratory of Molecular Biology, Cambridge

[2] Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham

来源：

NATURE | 1979年 / 279卷 / 5714期

关键词：

D O I：

10.1038/279607a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A three-dimensional image of tubulin protofilaments, reconstructed to 20 resolution from electron micrographs of negatively stained zinc-induced sheets, has been used to generate an improved model for microtubule substructure. This model has been used to phase a reconstructed image from x-ray amplitudes, which is compatible with the electron microscope results. © 1979 Nature Publishing Group.

引用

页码：607 / 612

页数：6

共 23 条

[1] AMOS L, 1979, MICROTUBULES
[2] AMOS LA, 1974, J CELL SCI, V14, P523
[3] ARRANGEMENT OF HIGH MOLECULAR-WEIGHT ASSOCIATED PROTEINS ON PURIFIED MAMMALIAN BRAIN MICROTUBULES
AMOS, LA
[J]. JOURNAL OF CELL BIOLOGY, 1977, 72 (03) : 642 - 654
[4] AMOS LA, UNPUBLISHED
[5] STRUCTURE OF TUBULIN DIMER IN ZINC-INDUCED SHEETS
BAKER, TS
AMOS, LA
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1978, 123 (01) : 89 - 106
[6] SUBUNIT ARRANGEMENT IN CILIARY MICROTUBULES FROM TETRAHYMENA-PYRIFORMIS
CHASEY, D
[J]. EXPERIMENTAL CELL RESEARCH, 1972, 74 (01) : 140 - &
[7] X-RAY DIFFRACTION FROM MICROTUBULES
COHEN, C
HARRISON, SC
STEPHENS, RE
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1971, 59 (02) : 375 - &
[8] X-RAY PATTERNS FROM MICROTUBULES
COHEN, C
DEROSIER, D
HARRISON, SC
STEPHENS, RE
THOMAS, J
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1975, 253 (JUN30) : 53 - 59
[9] DIFFERENCES IN ALPHA-POLYPEPTIDE AND BETA-POLYPEPTIDE CHAINS OF TUBULIN RESOLVED BY ELECTRON-MICROSCOPY WITH IMAGE-RECONSTRUCTION
CREPEAU, RH
MCEWEN, B
EDELSTEIN, SJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (10) : 5006 - 5010
[10] STRUCTURAL STUDIES ON PORCINE BRAIN TUBULIN IN EXTENDED SHEETS
CREPEAU, RH
MCEWEN, B
DYKES, G
EDELSTEIN, SJ
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1977, 116 (02) : 301 - 315

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