ION COUNTING AND ION INTENSITY MEASUREMENTS IN TIME-OF-FLIGHT MASS-SPECTROMETRY - APPLICATION TO MATRIX-ASSISTED LASER DESORPTION

被引：20

作者：

BAPTISTA, GB

BRUNELLE, A

CHAURAND, P

DELLANEGRA, S

DEPAUW, J

LEBEYEC, Y ^{[1
]}

机构：

[1] INST PHYS NUCL,F-91406 ORSAY,FRANCE

[2] PONTIFICIA UNIV CATOLICA RIO DE JANEIRO,DEPT FIS,BR-22453 RIO DE JANEIRO,BRAZIL

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1991年 / 5卷 / 12期

关键词：

D O I：

10.1002/rcm.1290051214

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A time-to-digital converter coupled to a charge-to-digital converter has been used to record mass spectra in matrix-assisted laser desorption (MALD) time-of-flight mass spectrometry. Masses above 100 000 Da have been detected by ion counting. Utilizing an electrostatic mirror, good mass resolution has been achieved in MALD. When the number of detected secondary ions is small the sensitivity of mass measurements is improved by using a charge-to-digital converter rather than a transient recorder.

引用

页码：632 / 637

页数：6

共 13 条

[1]

Beavis R C, 1989, Rapid Commun Mass Spectrom, V3, P436, DOI 10.1002/rcm.1290031208

[2]

Beavis R C, 1989, Rapid Commun Mass Spectrom, V3, P233, DOI 10.1002/rcm.1290030708

[3]

BEAVIS RC, IN PRESS METHODS MEC

[4] TIME-OF-FLIGHT MASS-SPECTROMETRY WITH A COMPACT 2-STAGE ELECTROSTATIC MIRROR - METASTABLE-ION STUDIES WITH HIGH MASS RESOLUTION AND ION EMISSION FROM THICK INSULATORS [J].