ORGANIC PHOSPHORUS-COMPOUNDS .96. RESOLUTION OF 1-AMINO-2-(4-FLUOROPHENYL)ETHYLPHOSPHONIC ACID AS WELL AS SOME DIPEPTIDES AND TRIPEPTIDES

被引：105

作者：

MAIER, L

SPORRI, H

机构：

[1] CIBA-GEIGY AG, Division Agro

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1991年 / 61卷 / 1-2期

关键词：

(+) AND (-) 1-AMINO-2-(4-FLUOROPHENYL)ETHYLPHOSPHONIC ACID; DIPEPTIDES; TRIPEPTIDES; BIOLOGICAL ACTIVITY;

D O I：

10.1080/10426509108027339

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Resolution of racemic l-amino-2-(4-fluorophenyl)ethylphosphonic acid with dibenzoyltartrate is easily accomplished. In the inhibition of PAL 2b(-) is about five times as active as 2a(+). The synthesis of the dipeptides 5a and 5b, and of the tripeptides 8a and 8b is described and comments are made on their biological activity. © 1991, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：69 / 75

页数：7

共 6 条

[1]

AMRHEIN N, COMMUNICATION

[2]

KAFARSKI P, 1985, BEITRAGE WIRKSTOFFOR

[3] SYNTHESIS, MOLECULAR-STRUCTURE, AND ABSOLUTE-CONFIGURATION OF AN OPTICALLY-ACTIVE (1-AMINO-2-PHENYLETHYL)PHOSPHONIC ACID MONOHYDRATE [J].