THE SEQUENCING OF THE 80-KDA D15 PROTECTIVE SURFACE-ANTIGEN OF HAEMOPHILUS-INFLUENZAE

被引:23
作者
FLACK, FS
LOOSMORE, S
CHONG, P
THOMAS, WR
机构
[1] INST CHILD HLTH RES,DIV MOLEC BIOL,PERTH,WA 6001,AUSTRALIA
[2] CONNAUGHT CTR BIOTECHNOL RES,N YORK,ON M2R 3T4,CANADA
关键词
CLONING; OUTER MEMBRANE PROTEIN; RADIOIMMUNOASSAY; PROTECTIVE IMMUNITY;
D O I
10.1016/0378-1119(95)00049-C
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The 80-kDa D15 antigen (D-15-Ag) has previously been shown to be a target for protective immunity and conserved amongst typeable and nontypeable Haemophilus influenzae. Here, the gene encoding D-15-Ag is shown to encode a 797-aa polypeptide which, after cleavage of the predicted signal peptide, would have a molecular mass of 85632 Da.
引用
收藏
页码:97 / 99
页数:3
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