HEPATIC-FAILURE IN A PATIENT TREATED WITH DACARBAZINE (DTIC) FOR MALIGNANT-MELANOMA

被引：31

作者：

FROSCH, PJ ^{[1
]}

CZARNETZKI, BM ^{[1
]}

MACHER, E ^{[1
]}

GRUNDMANN, E ^{[1
]}

GOTTSCHALK, I ^{[1
]}

机构：

[1] UNIV MUNSTER,INST PATHOL,D-4400 MUNSTER,FED REP GER

来源：

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY | 1979年 / 95卷 / 03期

关键词：

Chemotherapy; Dacarbazine; Liver failure; Malignant Melanoma; Toxicity;

D O I：

10.1007/BF00410649

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 55-year-old white woman received chemotherapy with DTIC after surgery for malignant melanoma (stage I, SSM IV, depth of invasion 12 mm). She died suddenly during the second treatment cycle. Autopsy revealed massive necrosis of the liver and thrombosis of the hepatic veins. The cause of the fatal outcome is attributed to the adverse toxic effects of DTIC. © 1979 Springer-Verlag.

引用

页码：281 / 286

页数：6

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