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METABOLISM, CYTO-TOXICITY, AND GENOTOXICITY OF THE PYRROLIZIDINE ALKALOID SENECIONINE IN PRIMARY CULTURES OF RAT HEPATOCYTES

被引：59
作者：
GREEN, CE
SEGALL, HJ
BYARD, JL
机构：
[1] UNIV CALIF DAVIS,DEPT ENVIRONM TOXICOL,DAVIS,CA 95616
[2] UNIV CALIF DAVIS,DEPT PHYSIOL SCI,DAVIS,CA 95616
来源：
TOXICOLOGY AND APPLIED PHARMACOLOGY | 1981年 / 60卷 / 02期
关键词：
D O I：
10.1016/0041-008X(91)90221-Y
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：176 / 185
页数：10
相关论文
共 43 条
[1]  
ANUFORO DC, 1978, IN VITRO CELL DEV B, V14, P981
[2]   PYRROLIZIDINE ALKALOIDS - THE BIOSYNTHESIS OF RETRONECINE [J].
BOTTOMLEY, W ;
GEISSMAN, TA .
PHYTOCHEMISTRY, 1964, 3 (02) :357-360
[3]   PYRROLIZIDINE ALKALOIDS AS ALKYLATING AND ANTIMITOTIC AGENTS [J].
CULVENOR, CC ;
DOWNING, DT ;
EDGAR, JA .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1969, 163 (A2) :837-+
[4]   HEPATOTOXICITY AND PNEUMOTOXICITY OF PYRROLIZIDINE ALKALOIDS AND DERIVATIVES IN RELATION TO MOLECULAR-STRUCTURE [J].
CULVENOR, CCJ ;
EDGAR, JA ;
JAGO, MV ;
OUTTERIDGE, A ;
PETERSON, JE ;
SMITH, LW .
CHEMICO-BIOLOGICAL INTERACTIONS, 1976, 12 (3-4) :299-324
[5]   METABOLISM OF AFLATOXIN-B1 IN CULTURED MOUSE HEPATOCYTES - COMPARISON WITH RAT AND EFFECTS OF CYCLOHEXENE OXIDE AND DIETHYL MALEATE [J].
DECAD, GM ;
DOUGHERTY, KK ;
HSIEH, DPH ;
BYARD, JL .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1979, 50 (03) :429-436
[6]   MAINTENANCE OF CYTOCHROME-P-450 AND METABOLISM OF AFLATOXIN-B1 IN PRIMARY HEPATOCYTE CULTURES [J].
DECAD, GM ;
HSIEH, DPH ;
BYARD, JL .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 78 (01) :279-287
[7]   EFFECTS OF A HORMONE-SUPPLEMENTED MEDIUM ON CYTOCHROME-P-450 CONTENT AND MONO-OXYGENASE ACTIVITIES OF RAT HEPATOCYTES IN PRIMARY CULTURE [J].
DICKINS, M ;
PETERSON, RE .
BIOCHEMICAL PHARMACOLOGY, 1980, 29 (09) :1231-1238
[8]   PRIMARY CULTURES OF ADULT-MOUSE AND RAT HEPATOCYTES FOR STUDYING THE METABOLISM OF FOREIGN CHEMICALS [J].
DOUGHERTY, KK ;
SPILMAN, SD ;
GREEN, CE ;
STEWARD, AR ;
BYARD, JL .
BIOCHEMICAL PHARMACOLOGY, 1980, 29 (15) :2117-2124
[9]   PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES [J].
DULBECCO, R ;
VOGT, M .
JOURNAL OF EXPERIMENTAL MEDICINE, 1954, 99 (02) :167-182
[10]   THE EFFECT OF PYRROLIZIDINE ALKALOIDS (SENECIO-VULGARIS) ON THE LIVER MIXED-FUNCTION OXIDASE SYSTEM [J].
EASTMAN, DF ;
SEGALL, HJ .
TOXICOLOGY LETTERS, 1980, 5 (06) :369-374
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