PARALLEL INDUCTION OF NITRIC-OXIDE AND GLUCOSE-6-PHOSPHATE-DEHYDROGENASE IN ACTIVATED BONE-MARROW-DERIVED MACROPHAGES

被引：30

作者：

CORRALIZA, IM ^{[1
]}

CAMPO, ML ^{[1
]}

FUENTES, JM ^{[1
]}

CAMPOSPORTUGUEZ, S ^{[1
]}

SOLER, G ^{[1
]}

机构：

[1] MAX PLANCK INST IMMUNBIOL,W-7800 FREIBURG,GERMANY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 196卷 / 01期

关键词：

D O I：

10.1006/bbrc.1993.2254

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The production of nitric oxide (NO·) and the induction of glucose-6-phosphate dehydrogenase by lipopolysaccharides (LPS) from different sources was studied in bone marrow derived macrophages (BMMϕ). NO· production was found to be linked to the induction of glucose-6-phosphate dehydrogenase, suggesting the possible involvement of this enzyme in the cytotoxic mechanism resulting from the release of NO· by activated macrophages. © 1993 Academic Press, Inc.

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页码：342 / 347

页数：6

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