HIGH-YIELD SYNTHESIS OF MONOSUBSTITUTED FERROCENES

被引：213

作者：

GUILLANEUX, D ^{[1
]}

KAGAN, HB ^{[1
]}

机构：

[1] INST CHIM MOLEC ORSAY,SYNTHESE ASYMETR LAB,CNRS,URA 1497,F-91405 ORSAY,FRANCE

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 08期

关键词：

D O I：

10.1021/jo00113a033

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The direct lithiation of ferrocene using an alkyllithium was widely explored and improved, but monolithioferrocene was never obtained fully devoid of 1,1'-dilithioferrocene. Pure (tri-n-butyl-stannyl)ferrocene was isolated in good yield from ferrocene (through the above lithiation). It can be stored and used (a) as an excellent precursor of pure monolithioferrocene, leading through reaction with many electrophiles to monosubstituted ferrocenes in nearly quantitative yields; (b) as a nucleophile in Stille cross-couplings with good results; (c) as a precursor of halogenoferrocenes through tin-halogen exchange.

引用

页码：2502 / 2505

页数：4

共 23 条

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