ON THE SUPERPOSITION OF CURRENTS FROM ION CHANNELS

被引：13

作者：

FREDKIN, DR ^{[1
]}

RICE, JA ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,DEPT MATH,LA JOLLA,CA 92093

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES | 1991年 / 334卷 / 1271期

关键词：

D O I：

10.1098/rstb.1991.0121

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We derive a number of statistical properties of the superposition of several independent channels contributing to a patch-clamp recording. Failure of these properties indicates dependence of the channels and may suggest the nature of interactions. We show how properties such as dwell-time distributions of the individual channels may be determined from those of the superposition in the case that the channels are independent.

引用

页码：347 / 356

页数：10

共 16 条

[1] STOCHASTIC PROPERTIES OF ION CHANNEL OPENINGS AND BURSTS IN A MEMBRANE PATCH THAT CONTAINS 2 CHANNELS - EVIDENCE CONCERNING THE NUMBER OF CHANNELS PRESENT WHEN A RECORD CONTAINING ONLY SINGLE OPENINGS IS OBSERVED [J].