Differential distribution of heterogeneous nuclear ribonucleoproteins in rat tissues

被引：18

作者：

Faura, M ^{[1
]}

RenauPiqueras, J ^{[1
]}

Bachs, O ^{[1
]}

Bosser, R ^{[1
]}

机构：

[1] UNIV BARCELONA, FAC MED, DEPT CELLULAR BIOL, E-08036 BARCELONA, SPAIN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 217卷 / 02期

关键词：

D O I：

10.1006/bbrc.1995.2811

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Heterogeneous nuclear ribonucleoproteins bind to RNA as long as it is transcribed. Since their binding can be sequence-specific, it has been suggested that their expression in different tissues could vary depending on the specific mRNA processing requirements. In order to better establish this possibility we studied the presence of the heterogeneous nuclear ribonucleoproteins Al, A2/B1, C and D in the cell nuclei of different rat tissues by one- and two-dimensional immunoblotting. We found that these proteins were heterogeneously distributed among tissues and that they were found in different proportions. (C) 1995 Academic Press, Inc.

引用

页码：554 / 560

页数：7

共 26 条

[1] IDENTIFICATION AND CHARACTERIZATION OF PACKAGING PROTEINS OF CORE 40S HNRNP PARTICLES [J].

BEYER, AL ;

CHRISTENSEN, ME ;

WALKER, BW ;

LESTOURGEON, WM .

CELL, 1977, 11 (01) :127-138

[2] HUMAN HNRNP PROTEIN-A1 GENE-EXPRESSION - STRUCTURAL AND FUNCTIONAL-CHARACTERIZATION OF THE PROMOTER [J].

BIAMONTI, G ;

BASSI, MT ;

CARTEGNI, L ;

MECHTA, F ;

BUVOLI, M ;

COBIANCHI, F ;

RIVA, S .

JOURNAL OF MOLECULAR BIOLOGY, 1993, 230 (01) :77-89

[3] PROTEIN-KINASE-C REGULATES CALMODULIN EXPRESSION IN NRK CELLS ACTIVATED TO PROLIFERATE FROM QUIESCENCE [J].

BOSCH, M ;

LOPEZGIRONA, A ;

BACHS, O ;

AGELL, N .

CELL CALCIUM, 1994, 16 (06) :446-454

[4]

BOSSER R, 1995, MOL CELL BIOL, V15, P661

[5]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[6] RNA-BINDING SPECIFICITY OF HNRNP A1 - SIGNIFICANCE OF HNRNP A1 HIGH-AFFINITY BINDING-SITES IN PRE-MESSENGER-RNA SPLICING [J].

BURD, CG ;

DREYFUSS, G .

EMBO JOURNAL, 1994, 13 (05) :1197-1204

[7] CALMODULIN EXPRESSION DURING PROLIFERATIVE ACTIVATION OF HUMAN T-LYMPHOCYTES [J].

COLOMER, J ;

AGELL, N ;

ENGEL, P ;

ALBEROLAILA, J ;

BACHS, O .

CELL CALCIUM, 1993, 14 (08) :609-618

[8] ISOLATION OF THE HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN COMPLEX (HNRNP) FROM VERTEBRATE NUCLEI [J].

DREYFUSS, G ;

CHOI, YD ;

ADAM, SA .

JOURNAL OF CELL BIOLOGY, 1984, 99 (04) :A233-A233

[9] HNRNP PROTEINS AND THE BIOGENESIS OF MESSENGER-RNA [J].

DREYFUSS, G ;

MATUNIS, MJ ;

PINOLROMA, S ;

BURD, CG .

ANNUAL REVIEW OF BIOCHEMISTRY, 1993, 62 :289-321

[10]

HAMILTON BJ, 1993, J BIOL CHEM, V268, P8881

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