A GENERAL-ROUTE FOR THE FACILE SYNTHESIS OF 4-THIOXOPYRIMIDIN-2-ONE DERIVATIVES VIA THE ANNULATION OF CYCLIC-ORTHO-AMINONITRILES USING CARBONYL SULFIDE

被引：8

作者：

HERNANDEZ, MA

CHUNG, FL

EARL, RA

TOWNSEND, LB

机构：

[1] UNIV MICHIGAN,COLL PHARM,DEPT MED CHEM,ANN ARBOR,MI 48109

[2] UNIV MICHIGAN,DEPT CHEM,ANN ARBOR,MI 48109

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1981年 / 46卷 / 20期

关键词：

D O I：

10.1021/jo00333a001

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3941 / 3945

页数：5

共 19 条

[1] NEW SYNTHESES OF PURINE [J].

BEAMAN, AG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (22) :5633-5636

[2]

CHACKE AA, 1965, THESIS U N CAROLINA

[3] SYNTHESIS OF CERTAIN [6-5-6] LINEAR TRICYCLIC NUCLEOSIDES AS POTENTIAL ANTI-TUMOR AGENTS [J].

CHUNG, FL ;

SCHRAM, KH ;

PANZICA, RP ;

EARL, RA ;

WOTRING, LL ;

TOWNSEND, LB .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (11) :1158-1166

[4]

CHUNG FL, 1980, TETRAHEDRON LETT, P1599

[5] HETEROCYCLEN AUS CH-ACIDEN NITRILEN .7. 2-AMINO-THIOPHENE AUS ALPHA-OXO-MERCAPTANEN UND METHYLENAKTIVEN NITRILEN [J].

GEWALD, K .

CHEMISCHE BERICHTE-RECUEIL, 1965, 98 (11) :3571-&

[6] 4-DIALKYLAMINOPYRIDINES AS ACYLATION CATALYSTS .4. 4-DIALKYLAMINOPYRIDINES AS HIGHLY ACTIVE ACYLATION CATALYSTS [J].

HOFLE, G ;

STEGLICH, W ;

VORBRUGGEN, H .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1978, 17 (08) :569-&

[7] DERIVATIVES OF NEW RING SYSTEM PYRAZOLO 4,3-D!-V-TRIAZINE AND SYNTHESIS OF 5,7-DISUBSTITUTED 3-METHYLPYRAZOLO 4,3-D!PYRIMIDINES AND 5,7-DISUBSTITUTED 3-METHYLPYRAZOLO 4,3-D!PYRIMIDINE 6-OXIDES WHICH ARE STRUCTURALLY RELATED TO NUCLEOSIDE ANTIBIOTICS FORMYCIN AND FORMYCIN-B [J].

LONG, RA ;

GERSTER, JF ;

TOWNSEND, LB .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1970, 7 (04) :863-&

[8] THE SYNTHESIS OF THIENO[2,3-D]PYRIMIDINE NUCLEOSIDES RELATED TO THE NATURALLY-OCCURRING NUCLEOSIDES CYTIDINE AND URIDINE [J].

PATIL, VD ;

WISE, DS ;

TOWNSEND, LB .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1980, (09) :1853-1858

[9] POTENTIAL PURINE ANTAGONISTS .1. SYNTHESIS OF SOME 4,6-SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDINES [J].

ROBINS, RK .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1956, 78 (04) :784-790

[10]

ROTIROTI LW, 1978, P AM ASSOC CANC RES, V19, P40

← 1 2 →