CENTRAL CHANGES IN HYPOTHYROID MYOPATHY - A CASE-REPORT

被引:19
作者
EVANS, RM
WATANABE, I
SINGER, PA
机构
[1] VET ADM MED CTR,NEUROL SERV,4801 LINWOOD BLVD,KANSAS CITY,MO 64128
[2] VET ADM MED CTR,LAB SERV,KANSAS CITY,MO 64128
[3] UNIV KANSAS,MED CTR,KANSAS CITY,KS 66103
关键词
central cores; hypothyroidism; muscle biopsy; myopathy; targetoid fibers;
D O I
10.1002/mus.880131011
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A muscle biopsy from a patient with hypothyroid myopathy showed striking central changes. “Cores” were seen in most type 1 fibers with oxidative enzyme prepartions. Electron microscopy of these areas revealed Z disc streaming, myofilament disruption, and absent mitochondria. The myopathy rapidly improved with thyroxine treatment. This biopsy is of interest, as numerous “cores” have not previously been reported in hypothyroid myopathy. Copyright © 1990 John Wiley & Sons, Inc.
引用
收藏
页码:952 / 956
页数:5
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