TRIPLE POSTTRANSCRIPTIONAL CONTROL

被引:17
作者
BECHHOFER, DH
机构
[1] Department of Biochemistry, Mount Sinai School of Medicine, New York, New York
关键词
D O I
10.1111/j.1365-2958.1990.tb02051.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ermC gene confers resistance to MLS antibiotics in a Bacillus subtilis host. Synthesis of the ermC gene product, a ribosomal RNA methylase, is inducible by the addition of subinhibitory concentrations of erythromycin. Regulation of ermC gene expression occurs at the post‐transcriptional level in three ways: translational attenuation, translational autoregulation, and messenger RNA stabilization. Copyright © 1990, Wiley Blackwell. All rights reserved
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页码:1419 / 1423
页数:5
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