TRIDIDEMNIC ACID-A AND ACID-B, AROMATIC ALKALOIDS FROM THE NORTHEASTERN PACIFIC ASCIDIAN TRIDIDEMNUM SP

被引：14

作者：

DESILVA, ED

MIAO, SC

ANDERSEN, RJ

SCHULTZ, LW

CLARDY, J

机构：

[1] UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 1Z4,BC,CANADA

[2] UNIV BRITISH COLUMBIA,DEPT OCEANOL,VANCOUVER V6T 1Z4,BC,CANADA

[3] CORNELL UNIV,BAKER LAB,DEPT CHEM,ITHACA,NY 14853

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 21期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ASCIDIAN; ALKALOID; TRIDIDEMNUM;

D O I：

10.1016/S0040-4039(00)79560-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new aromatic alkaloids, trididemnic acids A (1) and B (2), have been isolated from the marine ascidian Trididemnum sp. The structures of 1 and 2 were solved by spectroscopic analysis of their permethylated derivatives 4 and 5. Single crystal x-ray diffraction analysis of 4 confirmed the structures. An interesting retro-Fries rearrangement reaction, involving the conversion of 3 to 8 under bromination conditions, was also discovered.

引用

页码：2917 / 2920

页数：4

共 13 条

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