SUDDEN HEARING-LOSS ASSOCIATED WITH INTERFERON

被引：51

作者：

KANDA, Y

SHIGENO, K

KINOSHITA, N

NAKAO, K

YANO, M

MATSUO, H

机构：

[1] NAGASAKI CHUO NATL HOSP,DEPT OTOLARYNGOL,NAGASAKI,JAPAN

[2] NAGASAKI CHUO NATL HOSP,INST CLIN RES,NAGASAKI,JAPAN

[3] JAPANESE RED CROSS,NAGASAKI ATOM BOMB HOSP,DEPT OTOLARYNGOL,NAGASAKI,JAPAN

[4] JAPANESE RED CROSS,NAGASAKI ATOM BOMB HOSP,DEPT INTERNAL MED,NAGASAKI,JAPAN

[5] JAPANESE RED CROSS,NAGASAKI ATOM BOMB HOSP,DEPT NEUROL,NAGASAKI,JAPAN

来源：

LANCET | 1994年 / 343卷 / 8906期

关键词：

D O I：

10.1016/S0140-6736(94)90237-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

With the increasing long-term use of interferon, several new adverse effects have been recognised. We have prospectively assessed auditory function in 49 patients receiving interferon, after we saw a case of sudden sensorineural hearing loss during interferon therapy. Auditory disability (tinnitus, hearing loss, or both) occurred in 22 patients (45%) during treatment with audiometry-documented sensorineural hearing loss in 18 (37%). The auditory disability often developed in the late stage of treatment and resolved in all patients within 7-14 days after discontinuation of interferon.

引用

页码：1134 / 1135

页数：2

共 10 条

[1] BURMAN P, 1985, LANCET, V2, P100
[2] INTERFERON ENHANCES THE EXCITABILITY OF CULTURED NEURONS
CALVET, MC
GRESSER, I
[J]. NATURE, 1979, 278 (5704) : 558 - 560
[3] COLE RR, 1988, AM J OTOL, V9, P211
[4] CONLON KC, 1990, CANCER, V65, P2237, DOI 10.1002/1097-0142(19900515)65:10<2237::AID-CNCR2820651013>3.0.CO
[5] 2-5
[6] INTERFERON-ASSOCIATED RETINOPATHY
GUYER, DR
TIEDEMAN, J
YANNUZZI, LA
SLAKTER, JS
PARKE, D
KELLEY, J
TANG, RA
MARMOR, M
ABRAMS, G
MILLER, JW
GRAGOUDAS, ES
[J]. ARCHIVES OF OPHTHALMOLOGY, 1993, 111 (03) : 350 - 356
[7] INTERFERONS IN THE TREATMENT OF HUMAN CANCER
KIRKWOOD, JM
ERNSTOFF, MS
[J]. JOURNAL OF CLINICAL ONCOLOGY, 1984, 2 (04) : 336 - 352
[8] CLINICAL TOXICITY OF INTERFERONS IN CANCER-PATIENTS - A REVIEW
QUESADA, JR
TALPAZ, M
RIOS, A
KURZROCK, R
GUTTERMAN, JU
[J]. JOURNAL OF CLINICAL ONCOLOGY, 1986, 4 (02) : 234 - 243
[9] SIDE-EFFECTS OF ALPHA INTERFERON
RENAULT, PF
HOOFNAGLE, JH
[J]. SEMINARS IN LIVER DISEASE, 1989, 9 (04) : 273 - 277
[10] REVIEW - INTERFERONS AND AUTOIMMUNITY
SCHATTNER, A
[J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1988, 295 (06) : 532 - 544

← 1 →