SERUM VITAMIN-D CONCENTRATIONS AMONG ELDERLY PEOPLE IN EUROPE

被引:619
作者
VANDERWIELEN, RPJ
LOWIK, MRH
VANDENBERG, H
DEGROOT, LCPGM
HALLER, J
MOREIRAS, O
VANSTAVEREN, WA
机构
[1] TNO, NUTR & FOOD RES INST, ZEIST, NETHERLANDS
[2] F HOFFMANN LA ROCHE & CO LTD, CH-4002 BASEL, SWITZERLAND
[3] CSIC, INST NUTR, MADRID, SPAIN
关键词
D O I
10.1016/S0140-6736(95)91266-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vitamin D status decreases with age, mainly as a result of restricted sunlight exposure, reduced capacity of the skin to produce vitamin D, and reduced dietary Vitamin D intake. We measured wintertime serum 25-hydroxyvitamin D [25(OH)D] concentrations in 824 elderly people from 11 European countries. 36% of men and 47% of women had 25(OH)D concentrations below 30 nmol/L. Users of Vitamin D supplements and/or sunlamps had higher 25(OH)D (median 54 nmol/L) than non users (median 31 nmol/L). Surprisingly, lowest mean 25(OH)D concentrations were seen in southern European countries. Low 25(OH)D concentrations could largely be explained by attitudes towards sunlight exposure and factors of physical health status, after exclusion of users of vitamin D supplements or sunlamps. Problems with daily living activities and wearing clothes with long sleeves during periods of sunshine were strong predictors of low wintertime serum 25(OH)D concentrations. These findings show that free-living elderly Europeans, regardless of geographical location, are at substantial risk of inadequate Vitamin D status during winter and that dietary enrichment or supplementation with vitamin D should be seriously considered during this season.
引用
收藏
页码:207 / 210
页数:4
相关论文
共 31 条
  • [1] BERGSTEIN I, 1988, NED T DIETISTEN, V43, P169
  • [2] A NEW MECHANISM FOR INDUCED VITAMIN-D DEFICIENCY IN CALCIUM DEPRIVATION
    CLEMENTS, MR
    JOHNSON, L
    FRASER, DR
    [J]. NATURE, 1987, 325 (6099) : 62 - 65
  • [3] CRUZ JAA, 1991, EUR J CLIN NUTR, V45, P121
  • [4] EFFECT OF VITAMIN-D SUPPLEMENTATION ON WINTERTIME AND OVERALL BONE LOSS IN HEALTHY POSTMENOPAUSAL WOMEN
    DAWSONHUGHES, B
    DALLAL, GE
    KRALL, EA
    HARRIS, S
    SOKOLL, LJ
    FALCONER, G
    [J]. ANNALS OF INTERNAL MEDICINE, 1991, 115 (07) : 505 - 512
  • [5] DEGROOT CPG, 1988, 11 EUR REP
  • [6] VITAMIN-D NUTRITIONAL-STATUS AND RELATED BIOCHEMICAL INDEXES IN AN AUTONOMOUS ELDERLY POPULATION
    DELVIN, EE
    IMBACH, A
    COPTI, M
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1988, 48 (02) : 373 - 378
  • [7] AGE-DEPENDENT VITAMIN-D STATUS AND VERTEBRAL CONDITION OF WHITE WOMEN LIVING IN CURACAO (THE NETHERLANDS-ANTILLES) AS COMPARED WITH THEIR COUNTERPARTS IN THE NETHERLANDS
    DUBBELMAN, R
    JONXIS, JHP
    MUSKIET, FAJ
    SALEH, AEC
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1993, 58 (01) : 106 - 109
  • [8] SEASONAL FLUCTUATIONS IN SERUM CONCENTRATIONS OF VITAMIN-D METABOLITES IN NORMAL SUBJECTS
    JUTTMANN, JR
    VISSER, TJ
    BUURMAN, C
    DEKAM, E
    BIRKENHAGER, JC
    [J]. BRITISH MEDICAL JOURNAL, 1981, 282 (6273) : 1349 - 1352
  • [9] BONE-DENSITY PARATHYROID-HORMONE AND 25-HYDROXYVITAMIN-D CONCENTRATIONS IN MIDDLE-AGED WOMEN
    KHAW, KT
    SNEYD, MJ
    COMPSTON, J
    [J]. BRITISH MEDICAL JOURNAL, 1992, 305 (6848) : 273 - 277
  • [10] KLEINBAUM DG, 1982, EPIDEMIOLOGIC RES PR, P419