MOLECULAR-BASIS OF FACTOR-VIII INHIBITION BY HUMAN-ANTIBODIES - ANTIBODIES THAT BIND TO THE FACTOR-VIII LIGHT CHAIN PREVENT THE INTERACTION OF FACTOR-VIII WITH PHOSPHOLIPID

被引：160

作者：

ARAI, M ^{[1
]}

SCANDELLA, D ^{[1
]}

HOYER, LW ^{[1
]}

机构：

[1] AMER RED CROSS,BLOOD SERV,JEROME H HOLLAND LAB BIOMED SCI,ROCKVILLE,MD 20855

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1989年 / 83卷 / 06期

关键词：

D O I：

10.1172/JCI114107

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：1978 / 1984

页数：7

共 30 条

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[8] LOCALIZATION OF THE BINDING REGIONS OF A MURINE MONOCLONAL ANTI-FACTOR-VIII ANTIBODY AND A HUMAN ANTI-FACTOR-VIII ALLOANTIBODY, BOTH OF WHICH INHIBIT FACTOR-VIII PROCOAGULANT ACTIVITY, TO AMINO-ACID RESIDUES THREONINE-351-SERINE-365 OF THE FACTOR-VIII HEAVY-CHAIN [J].

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