VALIDITY OF THE MINI-MENTAL STATE EXAMINATION AS A SCREENING INSTRUMENT FOR COGNITIVE IMPAIRMENT AND DEMENTIA IN FRENCH ELDERLY COMMUNITY RESIDENTS

被引:108
作者
GAGNON, M
LETENNEUR, L
DARTIGUES, JF
COMMENGES, D
ORGOGOZO, JM
BARBERGERGATEAU, P
ALPEROVITCH, A
DECAMPS, A
SALAMON, R
机构
[1] Dèpartement de Neurologie de l’Hôpital Pellegrin, Bordeaux
[2] Unitè 1NSERM 169, Villejuif
[3] Centre de long sèjour gèriatrique, Lormont
关键词
Cognitive impairment; Epidemiology; Mini-Mental State examination; Prevalence; Screening instrument;
D O I
10.1159/000110764
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A survey was made of 2, 792 subjects aged 65 and older living in the community of Gironde (South-Western France). The predictive value of the Mini-Mental state examination (MMS) as a screening instrument for the detection of cognitive impairment was tested against DSM-III criteria for dementing syndromes. Of the 2, 792 subjects who consented to participate in the study, 101 met the DSM-III criteria for dementia, giving a 3.62% prevalence rate. With an MMS threshold of 24, the sensitivity was 100%, the specificity was 78%, and the positive predictive value was equal to 15%. Using the same MMS threshold, 572 subjects (85%) were false-positive for the diagnosis of dementia. A multiple logistic regression analysis revealed that age, sex, depressive symptomatology and educational level were independently correlated with false-positive cases of the MMS. Several issues are raised for using the MMS as the only screening instrument for cognitive impairment in elderly community residents. © 1990 S. Karger AG, Basel.
引用
收藏
页码:143 / 150
页数:8
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