POLYMORPHONUCLEAR ELASTASE IN NEONATAL SEPSIS

被引：20

作者：

TSAKA, T ^{[1
]}

HERKNER, KR ^{[1
]}

机构：

[1] LUDWIG INST PAEDIAT ENDOKRINOL,VIENNA,AUSTRIA

来源：

CLINICA CHIMICA ACTA | 1990年 / 193卷 / 03期

关键词：

Infection diagnosis; Neonatal disorder; Neonatal sepsis; Newborn; PMN-elastase;

D O I：

10.1016/0009-8981(90)90241-J

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Quantitative analysis of polymorphonuclear elastase was carried out in 135 newborn infants during the first 28 days of life. In 15 neonates with septicaemia, significantly increased PMN-elastase activity (range 75 to 700 μ1; P < 0.0001) was observed at the time of recognition of infection. Cut-off level 65 μ1. Normalisation of the elastase activities was observed only under real recovery of the patients. It is concluded that plasma elastase determination serves as a sensitive indicator of systemic infection in neonatology, and as a good parameter for monitoring the course of the disease, because PMN-elastase correlates with the clinical condition of the patient. © 1990.

引用

页码：103 / 111

页数：9

共 31 条

[1] ERYTHROCYTE SEDIMENTATION-RATE IN NEWBORN PERIOD [J].