GENETIC-CONTROL OF NICKEL SULFATE DELAYED-TYPE HYPERSENSITIVITY

被引：21

作者：

ISHII, N ^{[1
]}

ISHII, H ^{[1
]}

ONO, H ^{[1
]}

HORIUCHI, Y ^{[1
]}

NAKAJIMA, H ^{[1
]}

AOKI, I ^{[1
]}

机构：

[1] YOKOHAMA CITY UNIV,SCH MED,DEPT PATHOL,YOKOHAMA,KANAGAWA 232,JAPAN

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1990年 / 94卷 / 05期

关键词：

D O I：

10.1111/1523-1747.ep12876249

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Genetic control of delayed-type hypersensitivity (DTH) to nickel sulfate antigen was studied using various strains on inbred mice. Mice with class II Ad,k,s haplotypes showed a high magnitude of response, whereas those with class II Ab,f were low responders. These results indicate that nickel sulfate DTH may be influenced by the I-A region of H-2. Transfer experiments revealed that these responses might be mediated by L3T4+, Lyt-2-T cells. © 1990.

引用

页码：673 / 676

页数：4

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