CRYSTALLIZATION AND PRELIMINARY CHARACTERIZATION OF 3 CRYSTAL FORMS OF HUMAN RECOMBINANT TRANSFORMING GROWTH FACTOR-ALPHA

被引：2

作者：

DANISHEFSKY, AT ^{[1
]}

BURTON, LE ^{[1
]}

RUBIN, JR ^{[1
]}

机构：

[1] GENENTECH INC,DEPT PROC DEV,SAN FRANCISCO,CA 94010

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1992年 / 187卷 / 01期

关键词：

D O I：

10.1016/S0006-291X(05)81471-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three crystal forms of human recombinant TGF-α have been grown from solutions containing 2-methyl-2,4-pentanediol. One of the forms belongs to the orthorhombic space group C2221 and the other two belong to the monoclinic space group C2. Two of the crystal forms diffract to approximately 2.3Å Bragg spacings. X-ray diffraction data has been collected for all three forms. These data appear to be suitable for crystal structure determination, using either heavy atom isomorphous replacement methods or molecular replacement, for phase determination. © 1992 Academic Press, Inc.

引用

页码：146 / 151

页数：6

共 37 条

[1] LATTICES AND REDUCED CELLS AS POINTS IN 6-SPACE AND SELECTION OF BRAVAIS LATTICE TYPE BY PROJECTIONS [J].