BIOEQUIVALENCE

被引：63

作者：

RESCIGNO, A ^{[1
]}

机构：

[1] UNIV PARMA,SCH PHARM,I-43100 PARMA,ITALY

来源：

PHARMACEUTICAL RESEARCH | 1992年 / 9卷 / 07期

关键词：

BIOEQUIVALENCE; BIOAVAILABILITY; PLASMA CONCENTRATION FUNCTION; AUC;

D O I：

10.1023/A:1015809201503

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The bioequivalence of two formulations of the same drug may be determined by evaluating the similarity of their respective plasma concentration curves. The similarity of two plasma concentration functions can be measured by an index called the bioequivalence index. This paper shows how such an index may be defined and calculated.

引用

页码：925 / 928

页数：4