CAN LIVE ATTENUATED VIRUS WORK AS POSTEXPOSURE TREATMENT

被引：10

作者：

BONHOEFFER, S

NOWAK, MA

机构：

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 03期

关键词：

D O I：

10.1016/0167-5699(95)80129-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Simple mathematical models for the competition between different virus variants in the presence of a crossreactive immune response show that, contrary to expectation selection can favour variants that induce low viral loads. Here, Sebastian Bonhoeffer and Martin Nowak suggest that such 'competitively superior', but 'less pathogenic', mutants may be a possibility for post-exposure treatment of persistent virus infections.

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页码：131 / 135

页数：5

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