BENZODIAZEPINE AND SEDATIVE USE ABUSE BY METHADONE-MAINTENANCE CLIENTS

被引:116
作者
IGUCHI, MY
HANDELSMAN, L
BICKEL, WK
GRIFFITHS, RR
机构
[1] UNIV VERMONT,BURLINGTON,VT 05405
[2] JOHNS HOPKINS UNIV,SCH MED,BALTIMORE,MD 21205
[3] MT SINAI MED CTR,NEW YORK,NY 10029
关键词
BENZODIAZEPINES; BARBITURATES; SEDATIVES; METHADONE MAINTENANCE; DRUG ABUSE; DIAZEPAM; ALPRAZOLAM; LORAZEPAM;
D O I
10.1016/0376-8716(93)90090-D
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Clients at three geographically separate methadone maintenance clinics were surveyed regarding their lifetime use of ten commonly used benzodiazepines and barbiturates. In Baltimore (n = 50), 94% reported use of one or more of these drugs in their lifetime, with 66% reporting use in the last 6 months, In Philadelphia (n = 218), 78% reported use in their lifetime, with 53% reporting use in the last 6 months. In New York City (The Bronx) (n = 279), 86% reported use in their lifetime, with 44% reporting use in the last 6 months. Subjects reporting a history of use of at least 7 of 10 of the named sedatives were recruited for a more detailed interview. They reported that, among the benzodiazepines, diazepam, lorazepam, and alprazolam were frequently used for their 'high' producing effects, and for selling to produce income. In contrast, chlordiazepoxide, oxazepam, and phenobarbital, had much lower ratings of 'high' and were much less likely to be obtained for getting 'high' or for resale.
引用
收藏
页码:257 / 266
页数:10
相关论文
共 18 条
[1]   PREFERENCE FOR ALPRAZOLAM AS OPPOSED TO DIAZEPAM IN BENZODIAZEPINE-DEPENDENT PSYCHIATRIC-INPATIENTS [J].
APELT, S ;
SCHMAUSS, C ;
EMRICH, HM .
PHARMACOPSYCHIATRY, 1990, 23 (02) :70-75
[2]   FREQUENCY OF USE OF DIAZEPAM IN INDIVIDUALS ON PROBATION AND IN METHADONE-MAINTENANCE PROGRAMS [J].
BUDD, RD ;
WALKIN, E ;
JAIN, NC ;
SNEATH, TC .
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE, 1979, 6 (04) :511-514
[3]  
CIRAULO DA, 1988, J CLIN PSYCHIAT, V49, P333
[4]  
COACH WF, 1990, DHHS ADM911773 NIDA
[5]   TESTING THE ABUSE LIABILITY OF ANXIOLYTIC AND HYPNOTIC DRUGS IN HUMANS [J].
DEWIT, H ;
GRIFFITHS, RR .
DRUG AND ALCOHOL DEPENDENCE, 1991, 28 (01) :83-111
[6]  
Du Pont R.L., 1988, AM J DRUG ALCOHOL S1, V14, P1
[7]  
GRIFFITHS RR, 1990, J CLIN PSYCHOPHARM, V10, P237
[8]  
GRIFFITHS RR, 1987, PSYCHOPHARMACOLOGY 3
[9]   ALPRAZOLAM AND DIAZEPAM - ADDICTION POTENTIAL [J].
JUERGENS, S .
JOURNAL OF SUBSTANCE ABUSE TREATMENT, 1991, 8 (1-2) :43-51
[10]   DRUG-ABUSE PATTERNS OF PATIENTS ON METHADONE TREATMENT IN NEW-YORK-CITY [J].
KAUL, B ;
DAVIDOW, B .
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE, 1981, 8 (01) :17-25